The project “Developing a Wearable-Guided Paradigm for Deciphering a Personal Arrhythmogenic Chain in Paroxysmal Atrial Fibrillation (decipherAF)” will explore a wearable-guided paradigm for deciphering AF arrhythmogenic chains in individual patients.
The aim of the project is to develop freely available algorithmic tools for deciphering a personal arrhythmogenic chain in paroxysmal atrial fibrillation.
The project will contribute to answering questions that confront the understanding of the arrhythmogenic chain in individual patients: What is the path from acute exposures to atrial fibrillation occurrence? How should arrhythmogenic chains be deciphered, given that acute exposures occur outside the clinical setting? What are the capabilities of current wearables and what improvements are still necessary? These questions remain largely untouched, and their investigation will lay the foundations for new research directions.
Responding to global trends towards understanding the mechanisms that initiate atrial fibrillation, the “decipherAF” project aims to develop a wearable technology-based approach to deciphering individual patients’ arrhythmogenic circuits. Early atrial fibrillation detection is most beneficial not for applying potentially harmful drug treatment but rather for minimizing or delaying conventional treatment by focusing on an individual arrhythmogenic chain and involving targeted behavior change.
For more information on the project, please click here: decipherAF
The project “Non-invasive methods for monitoring cardio-renal function in heart failure patients (healtHFulness)” aims to develop non-invasive methods for monitoring heart failure status using physiological markers of cardio-renal function. Heart failure affects around 64.3 million people worldwide and is projected to increase as the population ages. The disease is associated with a high mortality rate and requires regular testing and medical assessment, which places a significant burden on the healthcare system. The two most common complications of heart failure are hemodynamic congestion and electrolyte imbalance. Unfortunately, these complications are silent until hospitalization is required, precluding the timely implementation of life-saving therapies. Physiological markers of cardio-renal function, such as electrolyte fluctuations and changes in body fluids, albeit unexplored in previous studies, are early manifestations of congestion and could be a viable approach to tracking heart failure progression.
The leader of the project dr. Andrius Rapalis notes that physiological parameters derived from biosignals may indirectly alter biomarkers and other pathophysiological changes associated with worsening heart failure, which would open up the possibility to monitor the disease outside the treatment facility.
For more information on the project, please click here: healtHFulness
The project „Development and integration of tools and technologies for post-stroke rehabilitation into clinical practice“ aims to develop new tools and technologies that, integrated into clinical practice, could significantly increase the effectiveness of post-stroke rehabilitation.
More than 12 million people suffer a stroke every year. It is estimated that about a quarter of all people will have a stroke in their lifetime. The project will develop a lightweight hip exoskeleton and adapt it to make walking easier for post-stroke hemiparesis sufferers.
According to the project leader, dr. Darius Jegelevičius, optimising rehabilitation by giving doctors, nurses and patients access to modern smart tools, increasing patient inclusion can help improve rehabilitation outcomes and reduce the human resources and financial costs required for nursing.
For more information on the project, please click here: link
