Biomedical Engineering Institute

KTU Biomedical Engineering Institute conducts research and experimental development in the areas of health monitoring, diagnostics, images, signals and medical information processing technologies. Its infrastructure, available prototyping equipment, the competences of researchers and scientists enable participation in international and national projects, development and testing of innovative prototypes, and provision of research services to businesses and medical institutions.

Research areas

Methods for bio signals processing

Adaptive and model-based parallel registered biomedical signals processing and applications for monitoring and diagnostics.

Physiological and biomechanical information sources and sensor investigation

New medical and biomechanical information sources, intelligent sensors and transducers and their wireless networks for physiology, movement analysis and ultrasonic (as well as nonlinear interactions) tissue for diagnosis, development and research.

Research of medical image processing methods and algorithms

Medical images processing based on models and parameterisation for increasing clinical value.

Research achievements and impact

Books

Alcaraz, Raúl; Corino, Valentina D. A.; Laguna, Pablo; Mainardi, Luca T.; Marozas, Vaidotas; Petrėnas, Andrius; Platonov, Pyotr G.; Rieta, José Joaquín; Sandberg, Frida; Sörnmo, Leif. Atrial fibrillation from an engineering perspective : [monograph] / editor: Leif Sörnmo. Cham : Springer, 2018. 316 p. PDF;

Lukoševičius, Arūnas. Bridging knowledge and economy: technology transfer and higher education // Higher education and national development: universities and societies in transition : [monograph] / edited by D. Bridges, P. Juceviciene, R. Jucevicius, T. McLaughlin, J. Stankeviciute. London : Routledge Taylor & Francis Group, 2007. PDF

Jurkonis, Rytis; Marozas, Vaidotas; Lukoševičius, Arūnas. Ultragarsinė medicininė diagnostika :praktiniai darbai su virtualiaisiais prietaisais : mokomoji knyga. Kaunas : Technologija, 2007. 95 p. PDF

Books Chapters

Patašius, Martynas; Marozas, Vaidotas; Jegelevičius, Darius; Lukoševičius, Arūnas; Kupčiūnas, Irmantas; Kopustinskas, Audris. Biomechanical modeling of blood vessels for interpretation of tortuosity estimates // Ophthalmological imaging and applications / Edited by E.Y.K. Ng, U. Rajendra Acharya, Rangaraj M. Rangayyan, Jasjit S. Suri. Boca Raton, FL : CRC Press, 2014. PDF

Petrėnas, Andrius; Marozas, Vaidotas; Lukoševičius, Arūnas; Sakalauskas, Andrius. Extraction of f-waves in electrocardiograms using echo state network based nonlinear adaptive filters // Digital Image and Signal Processing for Measurement Systems / Ed. by J. R. Duro, F. L. Pena. Aalborg : River Publishers, 2012. PDF

Doctoral Dissertations

Andrius Sološenko, „Cardiac Arrhythmia Detection in Photoplethysmogram Signals“, 2018 m., supervisor prof. Vaidotas Marozas. PDF

Andrius Rapalis, „Physiological Signal Processing Algorithms for Short-Term Heart Rate and Blood Pressure Variability Estimation“, 2017 m., supervisor dr. Artūras Janušauskas. PDF

Andrius Petrėnas, „Detection of Brief Episode Paroxysmal Atrial Fibrillation“, 2016 m., supervisor prof. Vaidotas Marozas. PDF

Andrius Sakalauskas, „Processing and Analysis of Transcranial Ultrasound Images“, 2016 m., supervisor prof. habil. dr. Arūnas Lukoševičius. PDF

Saulius Niauronis, „Investigation of Human Oculo-manual Coordination Control System“, 2014 m.,supervisor prof. habil. dr. Arūnas Lukoševičius. PDF

Raimondas Zemblys, „Informational Characteristic of Human Eye Sensorimotor System“, 2012 m., supervisor prof. habil. dr. Arūnas Lukoševičius.

Saulius Daukantas, „Investigation Of Multimodal Biosignals Registration and Analysis in Human Health Monitoring System“, 2012 m., supervisor prof. habil. dr. Arūnas Lukoševičius.

Vita Špečkauskienė, „Development and Analysis of Informational Clinical Decision Support Method“, 2011 m., supervisor prof. habil. dr. Arūnas Lukoševičius.

Martynas Patašius, „Automated Analysis of Eye Fundus Images“, 2011 m., supervisor prof. Vaidotas Marozas. PDF

Kristina Berškienė, „The Analysis of Dynamic Interrelationships of Electrocardiographic Signal Parameters“, 2010 m., supervisor prof. habil. dr. Arūnas Lukoševičius.

Ieva Sliesoraitytė, „Computer-Based Equipment and Hybrid Intraocular Pressure Control System“, 2008 m., supervisor prof. habil. dr. Arūnas Lukoševičius.

Skaidra Kurapkienė, „The Investigations of Electronic Technologies for Diagnostics of Eye Diseases“, 2006 m., supervisor prof. habil. dr. Arūnas Lukoševičius.

Darius Kybartas, „The Investigation of Coupled Modes in Piezoelements“, 2003 m., supervisor prof. habil. dr. Arūnas Lukoševičius.

Darius Jegelevičius, „Processing of Otalmological Diagnostic Signals in Telemedic Systems“, 2002 m., supervisor prof. habil. dr. Arūnas Lukoševičius.

Artūras Janušauskas, „Digital Signal Processing Techniques of Otoacoustic Emission Signals“, 2000 m., supervisor prof. habil. dr. Arūnas Lukoševičius.

Vaidotas Marozas, „Non-Linear Digital Filtering Of Biomedical Signals“, 2000 m., supervisor prof. habil. dr. Arūnas Lukoševičius. PDF

Rytis Jurkonis, „Investigation of Ultrasonic Medical Diagnostic Signal Temporary Transformations“, 2000 m., supervisor prof. habil. dr. Arūnas Lukoševičius.

Audrius Vaičiūnas, „Investigation and Optimization of Ultrasonic Medical Transducers Oscillation and Acoustics Fields“, 1996 m., supervisor prof. habil. dr. Arūnas Lukoševičius.

Kostas Vainauskas, „Research and Correction of Diffraction Errors in Pulsed Ultrasonic Measurement System“, 1989 m., supervisor prof. habil. dr. Arūnas Lukoševičius.

Journal Articles

Rapalis, Andrius; Petrėnas, Andrius; Šimaitytė, Monika; Bailón, Raquel; Marozas, Vaidotas. Towards pulse rate parametrization during free-living activities using smart wristband // Physiological measurement. Bristol : IOP Publishing. ISSN 0967-3334. eISSN 1361-6579. 2018, vol. 39, iss. 5, art. no. 055007, p. 1-12.

Marozas, Mindaugas; Zykus, Romanas; Sakalauskas, Andrius; Kupčinskas, Limas; Lukoševičius, Arūnas. Noninvasive evaluation of portal hypertension using a supervised learning technique // Journal of Healthcare Engineering. London : Hindawi. ISSN 2040-2295. eISSN 2040-2309. 2017, Vol. 2017, article 6183714, p. 1-10.

Paliakaitė, Birutė; Daukantas, Saulius; Marozas, Vaidotas. Assessment of pulse arrival time for arterial stiffness monitoring on body composition scales // Computers in biology and medicine. Oxford : Pergamon-Elsevier. ISSN 0010-4825. eISSN 1879-0534. 2017, vol. 85, p. 135-142.

Petrėnas, Andrius; Marozas, Vaidotas; Sološenko, Andrius; Kubilius, Raimondas; Skibarkienė, Jurgita; Oster, Julien; Sörnmo, Leif. Electrocardiogram modeling during paroxysmal atrial fibrillation: application to the detection of brief episodes // Physiological Measurement. Bristol : IOP Publishing. ISSN 0967- 3334. eISSN 1361-6579. 2017, Vol. 38, iss. 11, p. 2058-2080.

Rapalis, Andrius; Janušauskas, Artūras; Marozas, Vaidotas; Lukoševičius, Arūnas. Estimation of blood pressure variability during orthostatic test using instantaneous photoplethysmogram frequency and pulse arrival time // Biomedical signal processing and control. Oxford : Elsevier. ISSN 1746-8094. eISSN 1746-8108. 2017, Vol. 32, p. 82-89.

Rutkūnas, Vygandas; Gečiauskaitė, Agnė; Jegelevičius, Darius; Vaitiekūnas, Mantas. Accuracy of digital implant impressions with intraoral scanners. A systematic review // European Journal of Oral Implantology. Berlin : Quintessence Publishing Co. ISSN 1756-2406. eISSN 1756-2414. 2017, Vol. 10, iss. 1, p. 101-120.

Sološenko, Andrius; Petrėnas, Andrius; Marozas, Vaidotas; Sörnmo, Leif. Modeling of the photoplethysmogram during atrial fibrillation // Computers in biology and medicine. Oxford : Elsevier. ISSN 0010-4825. eISSN 1879-0534. 2017, Vol. 81, p. 130-138.

Ulozienė, Ingrida; Totilienė, Milda; Paulauskas, Andrius; Blažauskas, Tomas; Marozas, Vaidotas; Kaski, Diego; Ulozas, Virgilijus. Subjective visual vertical assessment with mobile virtual reality system // Medicina. Wrocław : Elsevier. ISSN 1010-660X. eISSN 1648-9144. 2017, vol. 53, no. 6, p. 394-402.

Zhao, Youbing; Parvinzamir, Farzad; Wilson, Stephen; Wei, Hui; Deng, Zhikun; Portokallidis, Nick; Third, Allan; Drosatos, George; Liu, Enjie; Dong, Feng; Marozas, Vaidotas; Lukoševičius, Arūnas; Kaldoudi, Eleni; Clapworthy, Gordon. Integrated visualisation of wearable sensor data and risk models for individualised health monitoring and risk assessment to promote patient empowerment // Journal of visualization. Berlin : Springer. ISSN 1343-8875. eISSN 1875-8975. 2017, vol. 20, iss. 2, p. 405-413.

Maciulevičius, Martynas; Tamošiūnas, Mindaugas; Jakštys, Baltramiejus; Jurkonis, Rytis; Venslauskas, Mindaugas Saulius; Šatkauskas, Saulius. Investigation of microbubble cavitation-induced calcein release from cells in vitro // Ultrasound in medicine and biology. New York, NY : Elsevier. ISSN 0301-5629. eISSN 1879-291X. 2016, vol. 42, iss. 12, p. 2990-3000.

Sakalauskas, Andrius; Laučkaitė, Kristina; Lukoševičius, Arūnas; Rastenytė, Daiva. Computeraided segmentation of the mid-brain in trans-cranial ultrasound images // Ultrasound in medicine & biology. Oxford : Elsevier. ISSN 0301-5629. eISSN 1879-291X. 2016, vol. 42, iss. 1, p. 322-332.

Jurkonis, Rytis; Lamanauskas, Nerijus; Šatkauskas, Saulius. Acoustic estimation of resonance frequency and sonodestruction of sonoVue microbubbles // Archives of ccoustics. Warszawa : Polish Academy of Sciences. ISSN 0137-5075. eISSN 2300-262X. 2015, vol. 40, iss. 3, p. 293-300.

Maciulevičius, Martynas; Tamošiūnas, Mindaugas; Jurkonis, Rytis; Venslauskas, Mindaugas; Šatkauskas, Saulius. Analysis of metrics for molecular sonotransfer in vitro // Molecular pharmaceutics. Washington, DC : ACS Publications. ISSN 1543-8384. eISSN 1543-8384. 2015, vol. 12, iss. 10, p. 3620-3627.

Petrėnas, Andrius; Marozas, Vaidotas; Jaruševičius, Gediminas; Sörnmo, Leif. A modified Lewis ECG lead system for ambulatory monitoring of atrial arrhythmias // Journal of electrocardiology. New York, NY : Churchill Livingstone. ISSN1532-8430. 2015, vol.48, no.2, p.157-163.

Petrėnas, Andrius; Marozas, Vaidotas; Sörnmo, Leif. Low-complexity detection of atrial fibrillation in continuous long-term monitoring // Computers in biology and medicine. Oxford : Pergamon-Elsevier. ISSN 0010-4825. 2015, vol. 65, p. 184-191.

Petrėnas, Andrius; Sornmo, Leif; Lukoševičius, Arūnas; Marozas, Vaidotas. Detection of occultparoxysmal atrial fibrillation // Medical & biological engineering & computing. Heidelberg : Springer. ISSN 0140-0118. eISSN 1741-0444. 2015, vol. 53, iss. 4, p. 287-297.

Petrolis, Robertas; Gintautas, Vladas; Kriščiukaitis, Algimantas. Multistage principal component analysis based method for abdominal ECG decomposition // Physiological measurement. Bristol : IOP Publishing. ISSN 0967-3334. eISSN 1361-6579. 2015, vol. 36, iss. 2, p. 329-340.

Sološenko, Andrius; Petrėnas, Andrius; Marozas, Vaidotas. Photoplethysmography-based method for automatic detection of premature ventricular contractions // IEEE transactions on biomedical circuits and systems. Piscataway, NJ : IEEE. ISSN 1932-4545. eISSN 1940-9990. 2015, vol. 9, iss. 5, p. 662-669.

Kriščiukaitis, Algimantas; Šimoliūnienė, Renata; Macas, Andrius; Petrolis, Robertas; Drėgūnas, Kęstutis; Bakšytė, Giedrė; Pieteris, Linas; Bertašienė, Zita; Žaliūnas, Remigijus. Detection and evaluation of ventricular repolarization alternans: An approach to combined ECG, thoracic impedance, and beat-to-beat heart rate variability analysis // Medicina. Wrocław : Elsevier. ISSN 1010-660X. 2014, vol. 50, no. 6, p. 345-352.

Laučkaitė, Kristina; Rastenytė, Daiva; Šurkienė, Danguolė; Vaidelytė, Birutė; Dambrauskaitė, Gabrielė; Sakalauskas, Andrius; Vaitkus, Antanas; Gleiznienė, Rymantė. Ultrasonographic (TCS) and clinical findings in overlapping phenotype of essential tremor and Parkinson’s disease (ET-PD) // BMC neurology. London : BioMed Central. ISSN 1471-2377. 2014, vol. 14, Article 54, p. 1-9.

Lukoševičius, Mantas; Marozas, Vaidotas. Noninvasive fetal QRS detection using an echo state network and dynamic programming // Physiological measurement. Bristol : IOP Publishing. ISSN 0967-3334. 2014, Vol. 35, iss. 8, p. 1685-1697.

Janušauskas, Artūras; Marozas, Vaidotas; Lukoševičius, Arūnas. Ensemble empirical mode decomposition based feature enhancement of cardio signals // Medical engineering & physics. Oxford : Elsevier Science. ISSN 1350-4533. 2013, Vol. 35, iss. 8, p. 1059-1069.

Sakalauskas, Andrius; Lukoševičius, Arūnas; Laučkaitė, Kristina; Jegelevičius, Darius; Rutkauskas, Saulius. Automated segmentation of transcranial sonographic images in the diagnostics of Parkinson’s disease // Ultrasonics. Amsterdam : Elsevier Science. ISSN 0041-624X. 2013, vol. 53, iss. 1, p. 111-121.

Jurkonis, Rytis; Janušauskas, Artūras; Marozas, Vaidotas; Jegelevičius, Darius; Daukantas, Saulius; Patašius, Martynas; Paunksnis, A.; Lukoševičius, Arūnas. Algorithms and results of eye tissues differentiation based on RF ultrasound // The scientific world journal. New York : Hindawi. ISSN 1537-744X. 2012, vol. 2012, p. [1-6].

Laučkaitė, Kristina; Rastenytė, Daiva; Šurkienė, Danguolė; Vaitkus, Antanas; Sakalauskas, Andrius; Lukoševičius, Arūnas; Gleiznienė, Rymantė. Specificity of transcranial sonography in Parkinson spectrum disorders in comparison to degenerative cognitive syndromes // BMC neurology. London : BioMed Central. ISSN 1471-2377. 2012, vol. 12, p. 1-8.

Petrėnas, Andrius; Marozas, Vaidotas; Sornmo, Leif; Lukoševičius, Arūnas. An echo state neural network for QRST cancellation during atrial fibrillation // IEEE Transactions on Biomedical Engineering. Piscataway, NJ : IEEE. ISSN 0018-9294. 2012, Vol. 59, iss. 10, article 33, p. 2950-2957.

Tamošiūnas, Mindaugas; Jurkonis, Rytis; Mir, Lluis M.; Lukoševičius, Arūnas; Venslauskas, Mindaugas; Šatkauskas, Saulius. Adjustment of ultrasound exposure duration to microbubble sonodestruction kinetics for optimal cell sonoporation in vitro // Technology in cancer research and treatment. Schenectady, NY : Adenine Press. ISSN 1533-0346. 2012, vol. 11, iss. 4, p. 375-387.

Tamošiūnas, Mindaugas; Jurkonis, Rytis; Mir, Lluis M.; Lukoševičius, Arūnas; Venslauskas, Mindaugas; Šatkauskas, Saulius. Microbubble sonodestruction rate as a metric to evaluate sonoporation efficiency // Journal of ultrasound in medicine. Laurel, MD : American Institute of Ultrasound in Medicine. ISSN 0278-4297. 2012, vol. 31, no. 12, p. 1993-2000.

Marozas, Vaidotas; Petrėnas, Andrius; Daukantas, Saulius; Lukoševičius, Arūnas. A comparison of conductive textile-based and silver/silver chloride gel electrodes in exercise electrocardiogram recordings // Journal of Electrocardiology. Philadelphia, PA : Churchill Livingstone Inc. Medical Publishers. ISSN 0022-0736. 2011, Vol. 44, iss. 2, p. 189-194.

Marozas, Vaidotas; Janušauskas, Artūras; Lukoševičius, Arūnas; Sornmo, Leif. Multiscale detection of transient evoked otoacoustic emissions // IEEE Transactions on Biomedical Engineering. New York : IEEE. ISSN 0018-9294. 2006, Vol. 53, no. 8, p. 1586-1593.

Paunksnis, Alvydas; Barzdžiukas, Valerijus; Jegelevičius, Darius; Kurapkienė, Skaidra; Dzemyda, Gintautas. The use of information technologies for diagnosis in ophthalmology // Journal of telemedicine and telecare : TeleMed and Health’05 : Meeting healthcare challenges. ISSN 1357-633X. 2006, vol. 12 Suppl. 1, p. 37-40.

Kviklienė, Adriana; Jurkonis, Rytis; Ressner, Marcus; Hoff, Lars; Jansson, Tomas; Janerot-Sjoberg, Brigitta; Lukoševičius, Arūnas; Ask, Per. Modelling of nonlinear effects and the response of ultrasound contrast micro bubbles: simulation and experiment // Ultrasonics. Oxford : Butterworth-Heinemann Ltd. ISSN 0041- 624X. 2004, Vol. 42, no. 1-9, p. 301-307.

Jansson, Tomas; Jurkonis, Rytis; Mast, T. Douglas; Persson, Hans W.; Lindstrom, Kjell. Frequency dependence of speckle in continuous-wave ultrasound with implications for blood perfusion measurements // IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control. New York : IEEE-Inst Electrical Electronics Engineers Inc. ISSN 0885-3010. 2002, Vol. 49, no. 6, p. 715-725.

Janušauskas, Artūras; Sornmo, Leif; Svensson, Owe; Engdahl, Bo. Detection of transient-evoked otoacoustic emissions and the design of time windows // IEEE Transactions on Biomedical Engineering. New York : IEEE. ISSN 0018-9294. 2002, Vol. 49, no. 2, p. 132-139.

Jurkonis, Rytis; Lukoševičius, Arūnas. New method of spatial superposition of attenuated waves for ultrasound field modelling // Ultrasonics. Amsterdam : Elsevier Science. ISSN 0041-624X. 2002, vol. 40, no. 1- 8, p. 823-827.

Petkus, Vytautas; Ragauskas, Arminas; Jurkonis, Rytis. Investigation of intracranial media ultrasonic monitoring model // Ultrasonics. Oxford : Butterworth-Heinemann Ltd. ISSN 0041-624X. 2002, Vol. 40, no. 1-8, p. 829-833.

Janušauskas, Artūras; Marozas, Vaidotas; Engdahl, B; Hoffman, H. J; Svensson, O; Sornmo, L. Otoacoustic emissions and improved pass/fall separation using wavelet analysis and time windowing // Medical & Biological Engineering & Computing. Herts. ISSN 0140-0118. 2001, Vol. 39, p. 134-139.

Significant publications

Henriksson, Mikael; Petrėnas, Andrius; Marozas, Vaidotas; Sandberg, Frida; Sörnmo, Leif. Model-based assessment of f-wave signal quality in patients with atrial fibrillation // IEEE Transactions on Biomedical Engineering. Piscataway : NJ : IEEE. 2018, Vol. 00, iss. 00. p. 1-12. Link

Petrėnas, Andrius; Sornmo, Leif; Lukoševičius, Arūnas; Marozas, Vaidotas. Detection of occult paroxysmal atrial fibrillation // Medical & biological engineering & computing. Heidelberg : Springer. ISSN 0140-0118. eISSN 1741-0444. 2015, vol. 53, iss. 4, p. 287-297. Link

Conferences

Zambacevičienė, Monika; Jurkonis, Rytis; Gelman, Sigita; Sakalauskas, Andrius. RF ultrasound based estimation of pulsatile flow induced microdisplacements in phantom // IFMBE Proceedings: World congress on medical physics and biomedical engineering 2018, June 3-8, 2018, Prague, Czech Republic.

Zambacevičienė, Monika; Jurkonis, Rytis. RF ultrasound based longitudinal motion estimation of carotid artery wall: feasibility study // IFMBE Proceedings: World Congress on Medical Physics and Biomedical Engineering 2018, June 3-8, 2018, Prague, Czech Republic

Alves, Dos Santos Rodrigues Ana Rita; Marozas, Vaidotas; Daukantas, Saulius; Kušleikaitė-Pere, Neda; Štramaitytė, Irmantė; Bumblytė, Inga Arūnė; Kaldoudi, Eleni. Differences between model-based electrocardiogram T wave features before and after haemodialysis // BIOCAS 2017 : IEEE Biomedical Circuits and Systems Conference (BioCAS), 19-21 October 2017, Torino, Italy.

Banerjee, Swati; Bailón, Raquel; Lazaro, Jesus; Marozas, Vaidotas; Laguna, Pablo; Gil, Eduardo. A two steps Gaussian modelling to assess PPG morphological variability induced by psychological stress // Computing in Cardiology (CinC): September 24-27, 2017, Rennes, France.

Henriksson, Mikael; Petrėnas, Andrius; Marozas, Vaidotas; Sandberg, Frida; Sörnmo, Leif. Signal quality assessment of f-waves in atrial fibrillation // Computing in Cardiology (CinC): September 24-27, 2017, Rennes, France.

Paliakaitė, Birutė; Petrėnas, Andrius; Skibarkienė, Jurgita; Mickus, Tomas; Daukantas, Saulius; Kubilius, Raimondas; Marozas, Vaidotas. Towards long-term monitoring of atrial fibrillation using photoplethysmography // BIOSTEC 2017 : Proceedings of the 10th International Joint Conference on Biomedical Engineering Systems and Technologies, Porto, Portugal, February 21-23, 2017.

Peralta, Elena.; Lázaro, Jesus; Gil, Eduardo; Bailón, Raquel; Marozas, Vaidotas. Robust pulse rate variability analysis from reflection and transmission photoplethysmographic signals // Computing in Cardiology (CinC): September 24-27, 2017, Rennes, France.

Sakalauskas, Andrius; Jurkonis, Rytis; Gelman, Sigita; Lukoševičius, Arūnas; Kupčinskas, Limas. Development of radiofrequency ultrasound based method for elasticity characterization using low frequency endogenous motion: phantom study // IFMBE Proceedings : EMBEC & NBC 2017 : Joint Conference of the European Medical and Biological Engineering onference (EMBEC) and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC), Tampere, Finland, June 2017.

Sološenko, Andrius; Petrėnas, Andrius; Marozas, Vaidotas; Sörnmo, Leif. Photoplethysmogram modeling during paroxysmal atrial fibrillation: detector evaluation // Computing in Cardiology (CinC): September 24-27, 2017, Rennes, France.

Lázaro, Jesús; Bailón, Raquel; Laguna, Pablo; Marozas, Vaidotas; Rapalis, Andrius; Gil, Eduardo. Difference in pulse arrival time at forehead and at finger as a surrogate of pulse transit time // Computing in cardiology conference (CinC). New York : IEEE. ISSN 2325-8861. 2016, vol. 43, p. 269-272.

Stanaitis, Skirmantas; Marozas, Mindaugas; Šileikaitė, Milda; Liutkevičienė, Rasa; Ulozas, Virgilijus; Marozas, Vaidotas; Ulozienė, Ingrida. Virtual reality based system for investigation of peripheral vestibular function // IFMBE Proceedings : XIV Mediterranean conference on medical and biological engineering and computing, MEDICON 2016, March 31st – April 2nd 2016, Paphos, Cyprus.

Stankevičius, Dainius; Petrėnas, Andrius; Sološenko, Andrius; Grigutis, Mantas; Januškevičius, Tomas; Rimševičius, Laurynas; Marozas, Vaidotas. Photoplethysmography-based system for atrial fibrillation detection during hemodialysis // IFMBE Proceedings : XIV Mediterranean conference on medical and biological engineering and computing, MEDICON 2016, March 31st – April 2nd 2016, Paphos, Cyprus.

Zhao, Youbing; Parvinzamir, Farzad; Wei, Hui; Liu, Enjie; Deng, Zhikun; Dong, Feng; Third, Allan; Lukoševičius, Arūnas; Marozas, Vaidotas; Kaldoudi, Eleni; Clapworthy, Gordon. Visual analytics for health monitoring and risk management in CARRE // E-learning and games : 10th international conference, edutainment 2016, Hangzhou, China, April 14-16, 2016.

Paliakaitė, Birutė; Daukantas, Saulius; Sakalauskas, Andrius; Marozas, Vaidotas. Estimation of pulse arrival time using impedance plethysmogram from body composition scales // 2015 IEEE : Sensors Applications Symposium (SAS), April 13-15, 2015, Zadar, Croatia.

Patašienė, Irena; Patašius, Martynas; Patašius, Juozas; Kregždytė, Rima. The set of simulations and games for improving citizens’ e-skills // Policy R(E)volution and every European digital : ONE Conference Brussels 2014.

Petrėnas, Andrius; Marozas, Vaidotas; Sornmo, L.; Jaruševičius, Gediminas; Gogolinskaitė, Deimantė. Modified Lewis ECG lrad system for ambulatory monitoring of atrial arrhythmias // Electrocardiology 2014 : 41st International Congress on Electrocardiology, June 4-7, 2014, Bratislava, Slovakia.

Sološenko, Andrius; Marozas, Vaidotas. Automatic extrasystole detection using photoplethysmographic signals // MEDICON 2013 : XIII Mediterranean conference on medical and biological engineering and computing 2013, 25-28 September, 2013, Seville, Spain.

Sološenko, Andrius; Marozas, Vaidotas. Automatic premature ventricular contraction detection in photoplethysmographic signals // Biomedical circuits and systems conference BIOCAS, 22-24 October 2014 EPFL, Lausanne, Switzerland.

Jurkonis, Rytis; Lukoševičius, Arūnas. Comparison of microsphere models for calculation of backscattered ultrasound spectra // International Symposium on Biomedical Engineering and Medical Physics, 10-12 October, 2012, Riga, Latvia.

Lukoševičius, Mantas; Marozas, Vaidotas. Noninvasive fetal QRS detection using echo state network // Computing in cardiology : 40th annual meeting on computing in cardiology (CinC), Zaragoza, Spain, September 22-25, 2013. New York, NY : IEEE. ISSN 2325-8861. eISSN 2325-887X. 2013, vol. 40, p. 205-208.

Petrėnas, Andrius; Sornmo, Leif; Marozas, Vaidotas; Lukoševičius, Arūnas. A noise-adaptive method for detection of brief episodes of paroxysmal atrial fibrillation // Computing in cardiology : 40th Annual meeting on computing in cardiology (CinC), Zaragoza, Spain, September 22-25, 2013. New York, NY : IEEE.

Petrėnas, Andrius; Marozas, Vaidotas; Sornmo, Leif; Lukoševičius, Arūnas. Reservoir computing for extraction of low amplitude atrial activity in atrial fibrillation // Computing in cardiology. New York, NY : IEEE. ISSN 0276-6574. 2012, vol. 39, p. 13-16.

Svilainis, Linas; Chaziachmetovas, Andrius; Jurkonis, Rytis; Kybartas, Darius; Lamanauskas, N.; Šatkauskas, S. The wideband ultrasonic pulser for sonoporation // Proceedings of 7th international conference on communications, electromagnetics and medical applications, Athens, Greece, 8-10 November, 2012 (CEMA’12) / Faculty of Telecomunications Technical University of Sofia, Bulgaria; National Technical University of Athens, Greece. School of electrical and computer engineering.

Svilainis, Linas; Chaziachmetovas, Andrius; Jurkonis, Rytis; Kybartas, Darius. Sonoporation generator design and performance evaluation // AIP Conference Proceedings : international congress on ultrasonics, 5–8 September 2011, Gdańsk, Poland. Melville, NY : AIP Publishing.

Daukantas, Saulius; Marozas, Vaidotas; Lukoševičius, Arūnas; Jegelevičius, Darius; Kybartas, Darius. Video and inertial sensors based estimation of kinematical parameters in swimming sport // The 6^th IEEE International Conference on Intelligent Data Acquisition and Advanced Computing Systems: Technology and Applications, 15-17 September, 2011, Prague, Czech Republic. Prague.

Kregždytė, Rima; Patašienė, Irena; Patašius, Martynas. Integration of multilevel health related data for generalized analysis // IFMBE Proceedings : 5th Europen Conference of the International Federation for Medical and Biological Engineering, 14-18 September, 2011, Budapest, Hungary. Berlin, Heidelberg, New York.

Patašius, Martynas; Marozas, Vaidotas; Jegelevičius, Darius; Lukoševičius, Arūnas. Finding initial points for drusen detection // IFMBE Proceedings : 5th Europen Conference of the International Federation for Medical and Biological Engineering, 14-18 September, 2011, Budapest, Hungary. Berlin.

Petrėnas, Andrius; Marozas, Vaidotas; Lukoševičius, Arūnas. Ventricular activity cancellation in ECG using and adaptive Echo State Network // The 6th IEEE International Conference on Intelligent Data Acquisition and Advanced Computing Systems: Technology and Applications, 15-17 September, 2011, Prague, Czech Republic.

Svilainis, Linas; Chaziachmetovas, Andrius; Kybartas, Darius; Jurkonis, Rytis. Advanced hardware for fine-tuning and optimization of sonoporation efficiency in vitro // IDAACS’2011 : proceedings of the 6^th International Conference on Intelligent Data Acquisition and Advanced Computing Systems: Technology and Applications, September 15-17, 2011, Prague, Czech Republic.

Svilainis, Linas; Jurkonis, Rytis; Kybartas, Darius; Chaziachmetovas, Andrius. High intensity acoustic pressure estimation using hydrophone and piezosensors // Proceedings of 6th International Conference on Communications, Electromagnetics and Medical Applications (CEMA’11), 6-8 October, 2011, Sofia, Bulgaria.

Petrėnas, Andrius; Marozas, Vaidotas; Daukantas, Saulius; Lukoševičius, Arūnas. Digital filter in hardware loop for on line ECG signal baseline wander reduction // IFMBE Proceedings : XII Mediterranean conference on medical and biological engineering and computing, MEDICON 2010, May 27-30, 2010, Chalkidiki, Greece.

Research infrastructure and services

Services provided by the Institute include applied scientific research, experimental development and studies of technical feasibility in the following areas:

Assessment of diagnostic and therapeutic equipment;
Medical electronics, wireless sensors and their networks, recording of multichannel biosignals streams, hardware design;
2D and 3D medical image processing, segmentation, modelling, parametrisation and classification;
Application and development of ultrasound diagnostic methods;
Processing of synchronously recorded multimodal biosignals and extraction of diagnostic information, development of new methods.

Available equipment

Medical visualisation equipment:
- Ultrasound scanner with full primary data collection (Ultrasonix);
- Ultrasound phantoms, amplifiers, transducers;
- Thermal imaging camera (FLIR).
Bio physiological signal acquisition equipment:
- Various sensors, multichannel amplifiers, primary signal acquisition and processing software;
- Breath gas analysis equipment.
Prototype production equipment:
- Soldering equipment;
- PCB production equipment (LPKF);
- Signal generators, oscilloscopes.
Testing equipment:
- Equipment for medical hardware technical assessment;
- Signal simulators.

KTU Open Access Centre

Technological solutions created by the Institute’s scientists and researchers help solve technological problems for business, industry and state companies. The R&D collaboration includes all stages of activity: from completing simple orders to first testing of prototypes and joint R&D projects of national and international importance.

All the services provided by Biomedical Engineering Institute and the equipment available for rent can be found on KTU Open Access Centre.

International

International Projects

EU FP7 Programme funded project “Personalized Patient Empowerment and Shared Decision Support for Cardiorenal Disease and Comorbidities -CARRE” (FP7-ICT-2013-611140), 2013-2016, supervisor prof. habil. dr. Arūnas Lukoševičius. Partners: Democritus University of Thrace (Greece) (leader partner); Knowledge Media Institute, The Open University (United Kingdom); University of Bedfordshire, (United Kingdom); Vilnius University Hospital Santariškių Klinikos (Lithuania); Industrial Research Institute for Automation and Measurements (Poland). Link

EU Baltic Sea Region Programme 2007-2013 funded project “Counteracting Brain Drain and Professional Isolation of Health Professionals in Remote Primary Health Care Through Tele-Consultation and Tele-Mentoring to Strengthen Social Conditions in Remote Baltic Sea Regions (PrimCareIT)”, 2012-2014, supervisor prof. habil. dr. Arūnas Lukoševičius. Partners: South Ostrobothnia Health Care District, Seinäjoki University of Applied Sciences, eHealth Institute, Linnaeus University Flensburg University of Applied Sciences Kaunas University of Technology Vilnius University Hospital Santariškiu Klinikos Lithuanian University of Health Sciences.

Swedish Institute, Visby Programme funded project “Novel Technical Solutions and Biomarkers in Mobile Patient Monitoring”, Agreement (No.00923/2011), 2011-2013, supervisor prof. Vaidotas Marozas. Coordinator: Lund university (prof. Leif Sornmo).

EU Baltic Sea Region Programme 2007-2013 funded project “Strengthening Social Capacities for the Utilisation of eHealth Technologies in the Framework of Ageing Population (ICTforHealth)”, 2009-2012, supervisor prof. habil. dr. Arūnas Lukoševičius. Coordinator: University of Applied Sciences Flensburg Department Hospital Management & eHealth (Germany). Partners: Aalborg University, Department of Development and Planning (Denmark); Region of South Denmark (Denmark); North Denmark Region (Denmark); Seinäjoki University of Applied Sciences (Finland); South Ostrobothnia Healthcare District (Finland); Regional Council of South Ostrobothnia (Finland); European Institute of Telemedicine e.V. (Germany); Institute for Cancer Epidemiology at the University of Luebeck (Germany); Diako-Hospital Flensburg (Germany); County Council of Segeberg (Germany);Association Health Forum Segeberg (Germany); Lithuanian University of Health Sciences (Lithuania); Kaunas University of Technology (Lithuania); Vilnius University Hospital Santariškių Klinikos (Lithuania); Diakonhjemmet Hospital (Norway); City Hospital Lebork (Poland); Hässleholm Hospital (Sweden); Pavlov State Medical University, St. Petersburg (Russia)

EUROSTARS E!4297 Programme funded project “A Non-Invasive Expert System for Diagnosis of Intraocular Tumours (NICDIT)”, 2008-2011, supervisor prof. habil. dr. Arūnas Lukoševičius.

EU FP7 Prpgramme funded project “Empowering Biomedical and Bioengineering SMEs to Promote Participation in FP7 Projects (SM-BIO-POWER)”, 2008-2011, supervisor prof. habil. dr. Arūnas Lukoševičius. Coordinator: Beacon Tech Ltd (Israel), partners: Fraunhofer institute for Factory Automation and Operation (Germany); Platinn (Switzerland); CENTRIM at the University of Brighton (United Kingdom); Lithuanian innovation Centre (Lithuania); Agenzia Perla Promozione della Ricerca Europea (Italy); University of Siena (Italy); The International Society for Professional Innovation Management (United Kingdom); Steinbeis Europa Zentrum (Germany).

EU FP6 Programme funded project “Speeding Collaborations in the Life Science and Health Domain of the European Research Area and Beyond (SPIDERA FOR LIFE)”, 2007-2009, supervisor prof. habil. dr. Arūnas Lukoševičius.

“Physiological Modelling of MR Image Formation” Project of EU Programme COST B21, funded by Agency of Lithuania International Programmes, 2007, supervisor prof. habil. dr. Arūnas Lukoševičius.

Project of EU Erasmus Virtual Campuses “European Virtual Campus for Biomedical Engineering (EVICAB)”, Contract (No. 2005-3868/001-001), 2006–2007, supervisor prof.habil. dr. Arūnas Lukoševičius. Coordinator: Tampere University (Finland), partners: Mediamaisteri Group (Finland); Tallinn University of Technology (Estonia); Linköping University (Sweden); Brno University of Technology (Czech Republic).

Common Project with Swedish institute and Linköping University “Ultrasound Dissemination in Medical Particles of Contrast Agents Research and Modelling”, supervisor prof. habil. dr. Arūnas Lukoševičius. Coordinator: Linköping University.

EU Interreg IIIC Programme funded project “Network for Future Regional Health Care (FutureHealth)”, (Reg. No. 2N0038N), 2004-2006, supervisor prof. habil. dr. Arūnas Lukoševičius. Coordinator: University of Helsinki and about 20 international partners.

Swedish Government funded (Baltic Billion Fund) project “Research and development of Electronic Health Record (LITMED II)”, 2003, supervisor prof. habil. dr. Arūnas Lukoševičius. Coordinator: Tieto Enator AB (Finland), partners: Kaunas Medical Academy (Lithunia); Lund University (Sweden); Informationslogic AB.

Swedish Government funded (Baltic Billion Fund) project “Pilot Medical Image Management System (MedWeb II)”, 2002-2003, supervisor prof. habil. dr. Arūnas Lukoševičius. Coordinator: Tieto Enator AB (Finland), partners: Kaunas Medical Academy (Lithunia); Lund University (Sweden); Informationslogic AB.

Common Project with Swedish institute and Lund University “Signal processing methods in medical information technology”, 2001-2003, supervisor prof. Arūnas Lukoševičius and prof. Leif Sörnmo (Lund University). Coordinator: Lund University (Sweden).

Swedish Government funded (Baltic Billion Fund) project “Research and development of a pilot telemedicine platform (LITMED)”, 2000-2002, supervisor prof. habil. dr.Arūnas Lukoševičius. Coordinator: Tieto Enator AB (Finland), partners: Kaunas Medical Academy (Lithuania); Stockholm St.Eric Eye Clinic (Sweden); Lund University (Sweden).

EU FP5 Programme funded Project “Telematic Support for Patient Focused Distant Care (Telemedicare)”, 2000-2002, supervisor prof. habil. dr. Arūnas Lukoševičius.

National

National Projects

EU Structural Funds funded project “Personalised Wearable Technologies for Evaluating Life-Threatening Health Conditions in Chronic Kidney Disease Patients (KidneyLife)“ (No. 01.2.2-LMT-K-718-01-0030), 2018–2022, supervisor Prof. Vaidotas Marozas. Coordinator Kaunas Universtity of Technology.

Research Council of Lithuania funded project “Ultrasound Radiofrequency Evaluation of Brain Tissue Properties for the Diagnosis of Early Neurodegeneration“ (No. S-MIP-17-17), 2017–2020, supervisor Dr. Andrius Sakalauskas. Coordinator: Lithuanian University of Health Sciences, partner: Kaunas University of Technology.

Research Council of Lithuania funded project “Detection and Parameterisation of the Changes in Eye Microcirculation Valuable for Diagnosis and Treatment of Critically Ill Patients (MAPEYE)“ (No. S-MIP-17-16), 2017–2019, supervisor Dr. Martynas Patašius. Coordinator: Lithuanian University of Health Sciences, partner: Kaunas University of Technology.

Research Council of Lithuania funded project “Methods for long-term unobtrusive monitoring of atrial arrhythmias in post-stroke patients (AfterStroke)“ (No. S-MIP-17-81), 2017–2019, supervisor Prof. Vaidotas Marozas. Coordinator: Kaunas University of Technology, partner: Vilnius University.

EU instrument Smart Invest LT+ funded project “Biomedical Electronic Equipment for Post-Stroke Monitoring (StrokeMonitor)“ (No. 01.2.1-LVPA-K-823-01-0004), 2016–2018, supervisor Dr. Darius Jegelevičius. Coordinator: Gruppo Fos Lithuania Company, partners: Kaunas University of Technology and Lithuanian University of Health Sciences.

Research Council of Lithuania funded project “Automatic algorithms for atrial fibrillation risk prediction after acute myocardial infarction (AFAMI)“ (No. MIP088), 2015–2017, supervisor Prof. Vaidotas Marozas. Coordinator: Kaunas University of Technology, partner: Lithuanian University of Health Sciences.

Institutional

Institutional Projects

A joint project of Kaunas University of Technology and Lithuanian University of Health Sciences“Assessment of early diabetes complications by analyzing multimodal data obtained through physiological tests (DiaSig)” (P22-184), supervisor prof. habil. dr. Arūnas Lukoševičius, 2018.

A joint project of Kaunas University of Technology and Lithuanian University of Health Sciences “Artery characterization study based on ultrasonic parametrization of intima-media movements (ArtU)” (P22-185), supervisor dr. Rytis Jurkonis, 2018.

A joint project of Kaunas University of Technology and Lithuanian University of Health Sciences “Investigation of elastic properties of liver tissue based on ultrasonic assessment of endogenous deformations (HepaCare III)”(PP27/176), supervisor dr. Andrius Sakalauskas, 2017.

A joint project of Kaunas University of Technology and Lithuanian University of Health Sciences “Creating and using a virtual reality stimulus in an innovative Vestibular System Test Device (VirVest)”(BN16-53), supervisor prof. Vaidotas Marozas, 2016.

A joint project of Kaunas University of Technology and Lithuanian University of Health Sciences “Development and application of non-invasive ultrasound diagnostic methods for liver fibrosis (HepaCareII)”(BN16-62), supervisor dr. Andrius Sakalauskas, 2016.

A joint project of Kaunas University of Technology and Lithuanian University of Health Sciences “Innovative research system for peripheral vestibular function estimation (InVest)”(SV5-6), supervisor prof. Vaidotas Marozas, 2015.

A joint project of Kaunas University of Technology and Lithuanian University of Health Sciences “Methods for innovative non-invasive methods for atrophic hypertension (HepaCare)”(BN15-95), supervisor dr. Rytis Jurkonis, 2015.